Elderberry Fruit Extract

Elderberry Fruit Extract

CAS No.: 84603-58-7
Latin Source: Sambucus nigra L.
Other Names: Caryophyllaceae, Sambucus sibiricum
Part Used: Fruit
Appearance: Dark Purple powder
Specification: 5%–25% anthocyanins
MOQ: 25 kg
Application: Dietary Supplements, Functional Health Foods
Certificates: Organic, cGMP, HACCP, FSSC22000, ISO9001, ISO22000, KOSHER, HALAL, FDA
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Description
Technical Parameters
Product Description

Elderberry fruit extract comes from the plant Sambucus nigra (scientific name: Sambucus nigra L.) of the Caprifoliaceae family. It is mainly distributed in the temperate and subtropical regions of the Northern Hemisphere, and is also distributed in Northeast China, North China, Northwest China, and other regions. The whole plant of elderberry is used as medicine. It is harvested in summer and autumn and can be used for extraction after drying.

Jiuyuan Biotech is a certified elderberry fruit extract manufacturer, offering bulk standardized Sambucus nigra extract with 5%–25% anthocyanins. Our elderberry extract is widely used in immune-support supplements, functional beverages, gummies, and nutraceutical formulations.

We provide high-quality, stable, and fully documented raw materials for food, beverage, and supplement manufacturers worldwide.

 

Health Benefits

 1. Immune Support

Elderberry fruit extract is best known for its role in supporting immune function.
Its anthocyanins and polyphenols may help:

  • Support the body's natural immune response
  • Promote healthy cytokine balance
  • Strengthen seasonal immune defense
  • Support upper respiratory wellness

These effects make elderberry extract a preferred ingredient for:
✔ immune gummies
✔ seasonal health formulas
✔ multivitamin blends
✔ immune beverage powders

 2. Antioxidant Protection

Elderberry is naturally rich in:

Anthocyanins; Polyphenols; Flavonols; Vitamin C

These compounds help neutralize free radicals and support overall antioxidant capacity, making the extract suitable for:

✔ anti-aging formulations
✔ cellular health supplements
✔ functional beverages
✔ beauty-from-within products

3. Anti-inflammatory Properties

Elderberry polyphenols may contribute to healthy inflammation regulation by:

  • Modulating oxidative stress
  • Supporting a balanced inflammatory response
  • Promoting joint & tissue wellness

This makes it a valuable ingredient for joint support blends or healthy-aging formulas.

4. Respiratory & Seasonal Wellness

Although elderberry is not a medicine, it is widely used in natural health products that aim to:

  • Support healthy respiratory function
  • Promote comfort during seasonal changes
  • Maintain throat & sinus wellness

This explains its popularity in:

cough & cold season gummies

immune drinks

herbal syrups

lozenges

5. Natural Colorant & Flavor Benefits

Beyond health effects, elderberry extract offers natural functional properties:

  • Deep purple color (anthocyanin-based)
  • Light berry flavor
  • Wellness-driven marketing appeal ("superfruit")

These characteristics make it a multifunctional ingredient for both health and food technology applications.

6. Gut & Digestive Health Support (Emerging Research)

Research suggests elderberry polyphenols may benefit gut wellness by:

  • Supporting a healthy gut microbiota balance
  • Acting as prebiotic-like polyphenols
  • Contributing to digestive comfort

 7. Cardiovascular & Metabolic Health (Polyphenol-Related Benefits)

Polyphenols in elderberry may help support:

Healthy blood vessel function

Antioxidant protection for cardiovascular wellness

Balanced metabolic function

These benefits make the extract suitable for broader wellness formulations, such as:

✔ heart health blends
✔ energy & vitality formulas
✔ anti-fatigue beverages

 

Certificate of Analysis

Item

Specification

Result

Method

Basic Product Information

     

Genus and Species

Sambucus nigra L.

   

Part of the Plant

Fruit

Conform

/

Country of Origin

China

Conform

/

Marker Compounds

     

Anthocyanidin(anthocyanin)

5.0%

5.2%

UV

Organoleptic Data

     

Appearance

Powder

Conform

Visual

Color

Dark purple

Conform

Visual

Odor

Characteristic

Conform

GB/T 5492-2008

Taste

Characteristic

Conform

GB/T 5492-2008

Process Data

     

Method of Processing

Extraction

Conform

/

Solvent(s) Used

Ethanol & Water

Conform

/

Drying Method

Spary drying

Conform

/

Physical Characteristics

     

Particle Size (80 mesh)

>99%pass 80 mesh

Conform

GB/T 5507-2008

Moisture

<5.0%

1.59%

GB/T 14769-1993

Ash Content

<4.0%

1.86%

AOAC 942.05, 18th

Heavy Metals

     

Total Heavy Metals

<10ppm

Conform

USP <231>, method II

As

<1.0ppm

Conform

AOAC 986.15, 18th

Pb

<1.0ppm

Conform

AOAC 986.15, 18th

Cd

<0.5ppm

Conform

AOAC 986.15, 18th

Hg

<0.5ppm

Conform

AOAC 971.21, 18th

Pesticide Residue

     

666

<0.2ppm

Conform

GB/T5009.19-1996

DDT

<0.2ppm

Conform

GB/T5009.19-1996

Microbiology

     

Total Plate Count

<10,000cfu/g

Conform

AOAC 990.12, 18th

Total Yeast & Mold

<1000cfu/g

Conform

FDA (BAM) Chapter 18, 8th Ed.

E. Coli

Negative

Negative

AOAC 997.11, 18th

Salmonella

Negative

Negative

FDA (BAM) Chapter 5, 8th Ed.

 

Key Features & Competitive Advantages

✔ Standardized High Anthocyanin Content (5%–25%)

Verified by HPLC to ensure consistent potency, color, and antioxidant activity.

✔ Multiple Grades Available

Spray-dried powder (5–15% anthocyanins) for beverages & gummies

Purified powder (18–25% anthocyanins) for capsules & tablets

Carrier-free grade optional for clean label formulations

✔ Stable Supply Chain

Raw materials sourced from EU-certified black elderberry farms, ensuring secure, year-round availability.

✔ Clean-Label, Non-GMO, No Artificial Additives

No synthetic colors, flavors, or preservatives.
Non-GMO, gluten-free, allergen-free.

✔ Fully Documented for Global Export

Including COA, MSDS, Non-GMO certificate, allergen statement, and more.

 

Applications & Usage Scenarios

1. Dietary Supplements

Popular for immune support and antioxidant formulations.
Ideal for:

  • Capsules

  • Tablets

  • Powders

  • Multivitamin blends

  • Recommended dosage: 1–5%

2. Functional Beverages

High solubility and natural purple color make it suitable for:

  • Instant beverage mixes

  • RTD drinks

  • Herbal drinks

  • Juice blends

  • Recommended dosage: 0.5–2%

3. Gummies & Functional Snacks

Natural flavor + color + antioxidant capacity.
Applications include:

  • Vitamin gummies

  • Nutraceutical candies

  • Fruit snacks

  • Recommended dosage: 2–6%

4. Natural Coloring & Food Ingredients

Used as a clean-label purple pigment for:

  • Bakery fillings

  • Yogurts

  • Frozen desserts

  • Cereal mixes

 

Production Process

Step Process Stage Description / Key Operations Purpose / Output
1 Raw Material Selection
Fresh ripe Sambucus nigra berries sourced from clean, traceable regions; inspected for color, moisture, and maturity. Ensure high anthocyanin and polyphenol content.
2 Cleaning & Sorting
Purified water washing, removal of stems/impurities; optical sorting for quality consistency. Obtain clean, uniform raw materials.
3 Crushing & Pulping Gentle crushing to release juice and active compounds; optional enzymatic treatment to increase yield. Improve extraction efficiency.
 
4 Water / Ethanol Extraction Low-temperature extraction using food-grade solvents (water/ethanol), depending on target specification (4:1 / 10:1 / 30% anthocyanins). Preserve heat-sensitive anthocyanins, flavonoids, and polyphenols.
 
5 Filtration & Purification Multi-stage filtration to remove seeds/fibers; purification to concentrate bioactives and stabilize color. Achieve high purity and concentrated actives.
 
6 Vacuum Concentration Low-heat vacuum evaporation to reduce moisture while protecting anthocyanins from oxidation. Obtain stable, concentrated elderberry extract.
 
7 Spray Drying Low-temperature spray drying to convert extract into powder; options for carrier-free or maltodextrin-supported drying. Produce stable, free-flowing elderberry powder.
 
8 Sieving & Blending Powder sieved to uniform mesh size (80–120 mesh); homogenized for consistent batch quality. Ensure stable solubility, color, and dispersion.
 
9 Final Quality Testing Testing for anthocyanin content (UV/HPLC), polyphenols, microbiological safety, pesticides, and heavy metals. Meet EU/US/Asia food-grade standards.
10 Packaging & Storage Packed in aluminum foil bags & fiber drums; optional nitrogen flush; stored in a cool, dry area.
Maintain stability, prevent oxidation, and extend shelf life.

jiuyuan biotech factory

 

Our Certifications

Production and operation licenses, cGMP, ISO9001 quality management system certification, ISO22000 food safety management system, HACCP certification, U.S. FDA inspection certification, halal certification, Kosher certification, etc. In the field of plant extract, Jiuyuan complies with relevant standards and requirements in the production, development, and sales links.

jiuyuan biotech certification

 

Comparison

Elderberry Fruit Extract vs. Other Immune-Support Botanical Extracts

This is the comparison your formulation team actually needs - not a generic "elderberry is good" table, but a frank look at where elderberry extract fits in the immune-support ingredient landscape relative to its closest competitors.

Ingredient

Primary Bioactive

Key Mechanism

Clinical Evidence

Consumer Recognition

Allergen

Vegan

Elderberry Extract (S. nigra)

Anthocyanins (cyanidin glycosides)

Antiviral, cytokine modulation, antioxidant

2 RCTs (influenza); multiple in vitro

Very high (mainstream)

None

✅

Echinacea Extract

Alkylamides, polysaccharides, caffeic acid derivatives

Innate immune stimulation, anti-inflammatory

Multiple RCTs; mixed outcomes

High

None

✅

Vitamin C (Ascorbic Acid)

Ascorbic acid

Antioxidant, leukocyte function support

Extensive; reduces cold duration modestly

Very high

None

✅

Zinc (Bisglycinate / Gluconate)

Zinc ion

Antiviral enzyme cofactor, T-cell function

Strong RCT evidence for cold duration

High

None

✅

Andrographis Extract

Andrographolide

NF-κB inhibition, antiviral

Several RCTs; strong for upper respiratory

Moderate (growing)

None

✅

Astragalus Extract

Polysaccharides, astragalosides

Adaptive immune modulation, T-cell support

Limited RCTs; mostly in vitro/animal

Moderate

None

✅

Beta-Glucan (Oat / Yeast)

β-1,3/1,6-glucan

Macrophage activation, innate immunity

Good RCT evidence

Moderate

Gluten risk (oat)

✅

The formulator's read: Elderberry extract occupies a unique position - it has the highest consumer recognition in the immune-support botanical category, a credible (if modest) clinical evidence base specifically for influenza, and a natural color contribution that no other immune botanical can offer. For brands building immune-support products with strong shelf appeal and consumer pull, it remains the anchor ingredient. For clinical-grade immune formulas, combining elderberry with zinc or andrographis provides complementary mechanisms and a stronger evidence stack.

S. nigra vs. S. canadensis - Which Species for Your Formula?

Parameter

Sambucus nigra (European)

Sambucus canadensis (American)

Anthocyanin content

Higher

Moderate

Anthocyanin stability

Standard

Higher (acylated anthocyanins)

Clinical research base

Extensive

Limited

Commercial availability

Widely available

Growing

Color stability in processing

Moderate

Better (heat/light)

Regulatory status (EU)

Well-established

Less documented

Best for

Supplements, clinical positioning

Beverages, food (color stability)

 

Delivery Methods

lQDPKGMvfZb4x23NAjzNA1qw2zuBMF7qYlcHLIUZvgIeAQ858572 lQDPJxnqnLSLN23NAjzNA1qwMj8Bbaib1ZwHLIUZvgIeAg858572 lQDPJwtZrxD2923NAjzNA1qwPujQkmzUYQgHLIUZvgIeAA858572

Express

Under 100kg, 3-5Days

Door-to-door service easy to pick up the goods

By Sea

Over300kg, Around 30 Days

Port-to-port service professional

clearance broker needed

By Air

100kg-1000kg, 5-7Days

Airport-to-airport service professional

clearance broker needed

 

Packaging Configuration

We offer three standard packaging formats, each designed around a specific order volume and transit risk profile:

Format

Net Weight

Inner Barrier

Outer Container

Nitrogen Flush

Best For

Sample Pack

100 g / 500 g

Double-sealed foil pouch

Cardboard box with desiccant

✅ Yes

R&D evaluation, pilot trials

Standard Unit

1 kg

Foil-laminated PE bag

Fiber drum (UN-certified)

✅ Yes

Small-batch production runs

Bulk Commercial

5 kg / 25 kg

Double-layer PE liner + foil outer

UN-certified fiber drum or aluminum canister

✅ Yes

Full-scale manufacturing

jiuyuan biotech warehouse

 

FAQ

Q1: How do I verify that your Elderberry fruit extract is genuine Sambucus nigra and not adulterated with cheaper anthocyanin sources?

This is the most important question a serious buyer can ask - and the fact that you're asking it is a good sign. Elderberry extract adulteration is a real and documented problem in the botanical ingredient supply chain. UV spectrophotometry measures total anthocyanin content but cannot distinguish elderberry anthocyanins from grape skin, black carrot, or blueberry anthocyanins. The only reliable identity verification method is HPLC-DAD or LC-MS/MS fingerprinting against authenticated S. nigra reference standards. Authentic S. nigra fruit extract is characterized by a cyanidin-dominant anthocyanin profile with cyanidin-3-sambubioside as the most abundant individual compound - a pattern that is distinct from common adulterants. We provide HPLC fingerprint data with every batch COA and actively encourage buyers to send samples to an ISO/IEC 17025-accredited third-party laboratory for independent confirmation.

Q2: What is the recommended dosage of Elderberry fruit extract for immune support applications?

Commercial immune support products using standardized elderberry extract typically deliver 300–600 mg of extract per day (standardized to 10–25% anthocyanins), based on the dosage ranges used in published clinical studies. The two most-cited RCTs - Zakay-Rones et al. (2004) and Tiralongo et al. (2016) - used elderberry syrup or capsule equivalents delivering approximately 600–900 mg of extract daily during acute illness. For daily maintenance immune support, lower doses (150–300 mg/day) are common in commercial products. Dosage should be aligned with your specific claim, target population, and regulatory requirements in your market. We provide substantiation documentation support for structure/function claims.

Q3: Is elderberry extract safe for children? Are there any known safety concerns?

Sambucus nigra ripe fruit and standardized fruit extracts have a well-established safety profile based on long-standing traditional use and available toxicological data. The primary safety consideration with elderberry is the distinction between ripe fruit (safe) and unripe fruit, leaves, bark, and seeds (contain sambunigrin, a cyanogenic glycoside that can cause nausea and vomiting). Our extract is produced exclusively from ripe fruit, and our process parameters are validated to ensure sambunigrin is not present at detectable levels in the finished extract. For children's products, we recommend the 5–10% anthocyanin grade at age-appropriate doses, and we provide full safety documentation including available toxicological data. As with any botanical ingredient in a children's formula, consult your regulatory counsel for market-specific labeling requirements.

Q4: How stable are anthocyanins in elderberry extract during formulation and shelf life?

Anthocyanin stability is the most technically demanding aspect of formulating with elderberry extract - and it's where many finished products underperform relative to their label claims. Anthocyanins are sensitive to heat, light, oxygen, and alkaline pH. In practical terms:

  • pH: Anthocyanins are most stable at pH ≤4.0 (red/pink form). Above pH 6.0, they undergo structural transformation and lose color and bioactivity. Beverage and gummy applications in acidic matrices are well-suited; neutral or alkaline formulas are challenging.
  • Heat: Avoid prolonged exposure above 60°C during processing. Spray drying is acceptable with optimized parameters.
  • Light: Finished products should use opaque or UV-blocking packaging. Amber glass or foil-laminate pouches are recommended.
  • Oxygen: Nitrogen flushing of packaging headspace significantly extends anthocyanin stability.

Our stability data (24-month real-time at 25°C/60% RH) is available on request and covers anthocyanin retention over the full shelf life period.

Q5: Can Elderberry fruit extract be used as a natural food colorant, and what color does it produce?

Yes - and this is an underutilized application that offers formulators a genuine dual-benefit opportunity: natural color and a functional ingredient claim in a single addition. Sambucus nigra anthocyanins produce a deep purple-red color in acidic matrices (pH ≤4.0), shifting toward blue-purple at higher pH values. In practical food applications, this means excellent color performance in:

  • Fruit beverages, juices, and RTD teas (naturally acidic)
  • Gummies and confectionery (typically acidic)
  • Yogurt and dairy (moderately acidic)
  • Kombucha and fermented beverages

The color is less stable than synthetic alternatives and requires appropriate packaging and processing controls. For applications requiring maximum color stability under heat and light, S. canadensis acylated anthocyanins offer improved performance. We can supply both subspecies depending on your application requirements.

Q6: Does elderberry extract interact with immunosuppressant medications?

This is a clinically relevant question for any brand formulating elderberry products for populations that may include transplant recipients or patients on immunosuppressive therapy. The theoretical concern is that elderberry's immune-stimulating properties (cytokine upregulation, NK cell activation) could potentially counteract immunosuppressant drugs. This interaction has not been documented in clinical case reports, but the mechanistic plausibility is sufficient to warrant a precautionary label advisory for individuals on immunosuppressive medications. We recommend consulting your regulatory and medical affairs team for appropriate label language in your target market. This is standard practice for immune-modulating botanical ingredients.

Q7: What is the difference between elderberry extract powder and elderberry juice concentrate? Which should I use?

These are distinct ingredient forms with different use cases:

Parameter

Elderberry Extract Powder

Elderberry Juice Concentrate

Anthocyanin content

Standardized (5–25%)

Variable (typically 1–5% in concentrate)

Consistency batch-to-batch

High (standardized)

Moderate (seasonal variation)

Dosage precision

High

Lower

Shelf life

24 months (dry powder)

12–18 months (refrigerated)

Formulation flexibility

High (capsules, tablets, gummies, powders)

Limited (liquid formats)

Cost per mg anthocyanin

Comparable or lower

Higher at equivalent anthocyanin dose

Label appeal

"Elderberry extract"

"Elderberry juice concentrate"

Best for

Supplements, functional food, cosmetics

Beverages, syrups, traditional formats

For supplement applications where dosage precision, batch consistency, and shelf stability are priorities, standardized elderberry extract powder is the appropriate choice. For traditional elderberry syrup formats where the "juice" positioning is part of the product story, concentrate may be preferred - though standardization to a defined anthocyanin content is still strongly recommended.

Q8: Do you offer custom extraction ratios or proprietary elderberry extract blends?

Yes. Our custom development capabilities include:

  • Custom anthocyanin standardization targets (e.g., 15%, 20%, or any intermediate specification)
  • Carrier-free high-potency extracts for maximum dose concentration in capsule formats
  • Elderberry + complementary botanical blends (e.g., elderberry + echinacea, elderberry + zinc, elderberry + vitamin C - pre-blended to your formula)
  • Organic-certified material (NOP and EU organic available for premium SKUs)
  • Water-soluble microencapsulated forms for enhanced stability in challenging formulation environments

Custom development requires a minimum order of 100 kg and a development lead time of 20–30 business days. Contact our technical team with your target specification and application context for a feasibility assessment and timeline.

 

Request a Sample or Commercial Quote

Jiuyuan Biotech supplies elderberry fruit extract to food manufacturers, supplement brands, and contract formulators across North America, Europe, and the Asia-Pacific region. Our technical team - not a generic sales inbox - handles every inquiry.

Email: info@jiuyuanbio.com

Website: www.jiuyuanbio.com

Request: Sample| Bulk Quote | CoA & Spec Sheet | Custom Carrier Ratio

Standard response time: within 1 business day. Please include your target application and annual volume estimate for the most relevant technical recommendation.

 

 

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