Organic Shiitake Extract Powder

Our Organic Shiitake Extract Powder is a high-quality botanical ingredient derived from carefully cultivated shiitake mushrooms (Lentinula edodes). As a leading manufacturer with over 13 years of experience in mushroom extraction, Shaanxi Jiuyuan Biotechnology provides a premium B2B solution for nutraceutical, functional food, and supplement manufacturers in the UK, USA, and beyond.

Our extract is produced under strict cGMP standards, ensuring batch-to-batch consistency, high purity, and traceable sourcing. Utilizing advanced extraction and drying technologies, we guarantee a product rich in polysaccharides, lentinan, and bioactive compounds that support immune health and overall wellness.

High Purity & Bioactive Content

• Contains 10–30% polysaccharides, with standardized lentinan content.

• Extracted from fruiting bodies, not mycelium, ensuring higher bioactivity.

• Free from additives, solvents, and artificial fillers.

Organic & Safe

• Certified Organic, HALAL, and KOSHER, suitable for international markets.
• Tested for heavy metals, pesticides, and microbial contamination.
• Safe for inclusion in dietary supplements, functional foods, and beverages.

Advanced Extraction Technology

• Utilizes hot water and ethanol dual extraction to maximize bioactive retention.
• Spray-dried or Air-dried powder available to meet different formulation requirements.
• Customizable mesh size (40–200 mesh) for specific applications.

Industrial-Scale Production & Supply

• Annual capacity over 6,000 tons, with 10 production lines.
• Supports bulk orders for capsule, tablet, gummy, powder blends, and functional food manufacturers.
• Consistent color, flavor, and solubility, suitable for mixing with other botanical ingredients.

Below is the COA of Organic Shiitake Extract Powder, please refer to it.

Shiitake mushroom has been valued for centuries in traditional medicine, and modern research confirms multiple health-promoting effects:

Immune System Support

• Polysaccharides, particularly lentinan, help modulate the immune response.

• Can enhance natural killer (NK) cell activity and support overall immune function.

Antioxidant Properties

• Rich in phenolic compounds and ergothioneine, helping to neutralize free radicals.

• Supports healthy aging and cellular protection.

Cardiovascular Health

• Beta-glucans may help maintain healthy cholesterol levels.

• Supports overall heart and vascular health when incorporated into functional foods.

Anti-inflammatory Effects

• Bioactive polysaccharides contribute to moderating inflammatory responses, beneficial in nutraceutical formulations.

Support for Gut Health

• Acts as a prebiotic, supporting beneficial gut microbiota.
• Can be formulated into functional drinks, capsules, or powder blends targeting digestive wellness.

Stage 1 - Organic Cultivation and Raw Material Sourcing

Our shiitake raw material comes from certified organic cultivation in the Qinling Mountain region of Shaanxi and select growing areas in Fujian Province - regions with documented shiitake cultivation histories spanning centuries.

Every incoming lot is tested for beta-glucan baseline content, heavy metals, pesticide residues, and microbial load before entering production. Lots failing any parameter are rejected.

Stage 2 - Fruiting Body Verification (Beta-Glucan Authenticity)

Before extraction, incoming material undergoes microscopic and chemical verification to confirm fruiting body predominance. This step is specifically designed to detect mycelium-on-grain adulteration - a pervasive quality issue in the functional mushroom ingredient supply chain .

Our verification protocol includes:

• Microscopic examination for hyphal morphology vs. grain starch granules
• Starch content screening (iodine test + enzymatic)
• Alpha-glucan vs. beta-glucan ratio assessment

Stage 3 - Hot Water Extraction

The primary extraction method for beta-glucan and lentinan recovery. Dried, milled fruiting body material is extracted in purified hot water:

• Temperature: 85–95°C (sufficient to solubilize high-molecular-weight beta-glucans including lentinan)
• Duration: 2–4 hours with continuous agitation
• pH: 6.0–7.5 (neutral conditions preserve polysaccharide chain integrity)
• Solid-to-liquid ratio: Optimized per incoming lot beta-glucan baseline

Hot water extraction is the method validated in the majority of clinical research on shiitake polysaccharides. It selectively recovers the water-soluble beta-glucan fraction while leaving behind insoluble chitin and lipid-soluble compounds .

Stage 4 - Dual Extraction (Full-Spectrum Grade)

For full-spectrum grades, a secondary ethanol extraction step follows hot water extraction. This recovers alcohol-soluble triterpenes, sterols (including ergosterol/vitamin D precursor), and eritadenine - compounds not captured by water extraction alone.

The two extracts are combined and concentrated to produce a full-spectrum powder that retains both the water-soluble polysaccharide fraction and the ethanol-soluble bioactive fraction.

Stage 5 - Filtration, Concentration, and Spray Drying

The extract undergoes sequential filtration (coarse → fine → membrane) to remove particulates. The clarified extract is concentrated under vacuum at ≤60°C, then spray-dried at calibrated parameters to achieve target moisture content (≤5%).

Stage 6 - Standardization and Release Testing

The dried powder is blended to specification and held for full release testing - including Megazyme beta-glucan assay - before batch approval. No batch ships without a confirmed Megazyme result.

Our organic shiitake mushroom extract powder is highly versatile and widely used across various sectors:

1. Nutraceuticals & Supplements

• Capsules, tablets, gummies, effervescent powders.

2. Functional Foods & Beverages

• Protein bars, tea blends, soups, health drinks.

• Supports claims like "immune support," "antioxidant protection," and "natural wellness."

3. Cosmetic & Skincare Products

• Anti-aging formulations, skin vitality supplements.

• Utilizes antioxidants and polysaccharides to support skin health from within.

4. Research & Development

• Universities, laboratories, and biotech companies use our extract for preclinical studies.
• Provides a reliable, standardized source of bioactive compounds for scientific research.

This comparison addresses the questions that experienced mushroom ingredient buyers ask - and that most suppliers avoid answering directly :

The bottom line: mycelium-on-grain products are the most prevalent quality problem in the functional mushroom ingredient category. The starch from the grain substrate inflates UV polysaccharide figures dramatically. Megazyme beta-glucan testing exposes this discrepancy. Any supplier unwilling to provide Megazyme data alongside UV polysaccharide figures should be treated with caution.

Trusted Manufacturer & Supplier

• Over 13 years of experience producing high-quality mushroom extracts.
• Transparent traceability from farm to finished product.

Comprehensive Certifications

• Organic, cGMP, ISO9001, ISO22000, HACCP, FSSC22000, HALAL, KOSHER.
• Ensures compliance with global international import regulations.

Flexible Packaging & Logistics

• Packaging options: 1kg, 5kg, 10kg, or customized for bulk orders.
• Supports air freight, sea freight, and express shipping to international clients.

Customizable Extraction & Formulation

• Polysaccharide content adjustable (10–50%).
• Particle size tailored to capsule, tablet, or instant beverage applications.

Packaging Configuration

We offer three standard packaging formats, each designed around a specific order volume and transit risk profile:

Standard Transit Options:

Q1: What is the difference between polysaccharide content and beta-glucan content - and which number should I put on my label?

Total polysaccharides (measured by UV) include all sugar polymers in the extract - beta-glucans, alpha-glucans (starch), and other polysaccharide fractions. Beta-glucans (measured by Megazyme) specifically quantify the (1→3),(1→6)-β-D-glucan fraction responsible for immunomodulatory activity . For supplement label claims, beta-glucan content verified by Megazyme is the defensible figure. Total polysaccharide figures without Megazyme confirmation are increasingly scrutinized by retailers, third-party certifiers, and regulatory bodies. We recommend labeling beta-glucan content specifically.

Q2: Why do you insist on fruiting body over mycelium-on-grain?

Lentinan is produced in the fruiting body of Lentinus edodes - not in mycelium grown on grain substrates. Mycelium-on-grain products contain the grain substrate (typically rice or oats) as a significant portion of the final powder, contributing starch that inflates UV polysaccharide figures without adding biological activity. Multiple independent analyses have found beta-glucan content in mycelium-on-grain products to be 1–5% by Megazyme - compared to 10–30% in genuine fruiting body extracts . Our organic cultivation uses hardwood substrates, and fruiting body predominance is verified by microscopy and enzymatic starch screening on every incoming lot.

Q3: Is lentinan stable through standard supplement manufacturing processes?

Lentinan's triple-helix conformation - the structural feature responsible for its biological activity - is disrupted by temperatures above 100°C and strongly acidic conditions (pH below 3). Standard tablet compression and encapsulation processes do not involve these conditions, so lentinan integrity is maintained in finished supplements. For beverage applications involving pasteurization or UHT processing, we recommend consulting our technical team on heat stability data for specific processing parameters.

Q4: Does your organic shiitake extract contain vitamin D?

Ergosterol (provitamin D₂) is present in our shiitake extracts. However, conversion of ergosterol to vitamin D₂ (ergocalciferol) requires UV irradiation - a step that does not occur during our standard low-temperature drying process. Our standard grades contain ergosterol but not significant vitamin D₂. UV-activated grades - where dried mushroom material is exposed to controlled UV irradiation before extraction - are available on request and carry vitamin D₂ content verified by HPLC.

Q5: How does shiitake extract compare to other functional mushrooms like reishi or lion's mane for immune applications?

Each functional mushroom has a distinct bioactive profile. Shiitake's primary differentiator is lentinan - a species-specific beta-glucan with the most extensive clinical research of any mushroom polysaccharide, including pharmaceutical-level studies in Japan . Reishi (Ganoderma lucidum) is characterized by triterpene ganoderic acids alongside beta-glucans, with broader adaptogenic positioning. Lion's mane (Hericium erinaceus) is primarily studied for nerve growth factor (NGF) stimulation via hericenones and erinacines, making it more relevant to cognitive health formulas. For immune-specific formulations, shiitake's lentinan content gives it a distinct clinical evidence advantage. We supply all three mushroom extracts and can advise on combination formulations.

Q6: What documentation do you provide for EU organic supplement compliance?

For EU market entry with organic claims, we provide: EU Organic certificate (current, with validity dates), organic transaction certificate (batch-specific), full COA with Megazyme beta-glucan data, ICP-MS heavy metal report, GC-MS/MS pesticide residue report compliant with EU MRLs for food supplements, and FSSC 22000 food safety certificate. We can also provide a technical dossier supporting Novel Food status assessment if required for your specific product format.

Q7: Can I get a custom blend of shiitake with other functional mushrooms?

Yes. We supply reishi, lion's mane, chaga, turkey tail, cordyceps, and maitake extracts alongside shiitake, and offer custom blended powders in specified ratios. Custom blends are tested for each component's beta-glucan or primary active content individually, with a combined COA. Minimum order quantities for custom blends start at 25 kg of finished blend. Contact our technical team to discuss target specifications and ratios.

Q8: How do you handle heavy metal risk specific to mushroom cultivation?

Mushrooms bioaccumulate heavy metals from their growth substrate more efficiently than most plant species. Our risk management operates at three levels: (1) farm-level soil and substrate testing before cultivation begins; (2) incoming lot ICP-MS testing for Pb, As, Hg, and Cd on every lot before production entry; (3) finished product ICP-MS testing on every batch before release. We do not rely on periodic or annual heavy metal testing - every batch is individually verified. Our arsenic specification (≤1 ppm) and lead specification (≤0.5 ppm) are set below the thresholds that would trigger Prop 65 warnings at standard supplement serving sizes.

Jiuyuan Biotech supplies Organic Shiitake Extract Powder to immune health formulators, functional mushroom brands, contract manufacturers, and supplement companies across 30+ countries. Our technical team advises on grade selection, Megazyme beta-glucan specifications, organic certification requirements, and custom mushroom blend formulations.

Contact us to receive:

Batch-specific COA with Megazyme beta-glucan data

1 kg R&D sample (shipping cost applies)

Pricing for standard, high-potency, full-spectrum, and organic grades

Third-party pesticide and heavy metal test reports

Custom mushroom blend specifications

Factory audit scheduling (in-person or live video)

📧 info@jiuybiotech.com | 🌐 www.jiuyuanbio.com