Mulberry Leaf Extract

Our premium Mulberry Leaf Extract, derived from the finest Morus alba L. leaves, is meticulously processed using advanced extraction techniques to ensure the highest purity and potency. We offer a range of standardized extracts, featuring key active ingredients such as 1-Deoxynojirimycin (1-DNJ) at concentrations of 1% to 10%, polysaccharides at 20% and 30%, and flavonoids at 5% and 8%. These components are crucial for various applications, including nutraceuticals, pharmaceuticals, and functional foods. 1-DNJ is particularly valued for its blood glucose regulation properties, making it ideal for diabetes management products. Polysaccharides and flavonoids offer antioxidant and anti-inflammatory benefits, suitable for dietary supplements and skincare formulations. Our extract caters to clients seeking high-quality, reliable ingredients for their innovative product development. We adhere to stringent quality control standards, ensuring consistent and superior product performance.

Shaanxi Jiuyuan Biological Co., Ltd. is committed to providing Mulberry Extract that adheres to the highest international standards. Our products are certified by multiple internationally recognized bodies, including ISO 9001, ISO 22000, GMP (Good Manufacturing Practice), and HACCP (Hazard Analysis and Critical Control Points). These certifications not only attest to the superior quality of our products but also reflect our stringent management practices and unwavering pursuit of product excellence.

Raw Material Sourcing: We meticulously select premium mulberry leaves as our raw material, sourced exclusively from rigorously vetted suppliers. Our mulberry cultivation bases employ green farming practices, free from pesticides and chemical fertilizers, ensuring the purity and safety of our raw materials. Furthermore, we implement sustainable cultivation and procurement measures, such as crop rotation, soil health preservation, and water resource conservation, to guarantee a stable long-term supply of raw materials while safeguarding the ecological environment.
 

Production Process: Utilizing advanced extraction and purification technologies, we ensure the high purity and potency of our extracts. Our meticulously optimized production processes maximize the retention of valuable mulberry leaf components, including 1-Deoxynojirimycin (DNJ) and flavonoid compounds. Our unique extraction techniques enable us to achieve DNJ concentrations exceeding 10%, significantly surpassing industry averages.
 

Testing Procedures: We maintain a comprehensive quality testing system, conducting rigorous inspections at every stage, from raw material procurement to final product release. Employing advanced analytical techniques, such as High-Performance Liquid Chromatography (HPLC) and Ultraviolet-Visible Spectrophotometry (UV), we ensure that our products' composition and quality consistently meet international standards.

Safety Data: We provide detailed safety test reports, including assessments for heavy metals (e.g., lead, cadmium, mercury, arsenic), pesticide residues, and microbial contaminants (e.g., E. coli, Salmonella). Our products consistently meet international safety standards across all test parameters, ensuring complete product safety.

Stability: Our Mulberry Extract exhibits exceptional stability under various storage conditions. Through rigorous stability testing, we guarantee that the active ingredient content remains consistent throughout the product's shelf life when stored at room temperature, in dry conditions, and away from light, fulfilling our clients' long-term storage requirements.

Raw Material Inspection: Each batch of mulberry leaf raw material undergoes a thorough inspection to ensure compliance with quality standards.
Production Process Monitoring: Real-time monitoring of critical parameters during production ensures process stability.
Finished Product Testing: Multiple rounds of testing, including composition analysis, heavy metal detection, and pesticide residue screening, are conducted on the finished product to ensure compliance before release.
Customer Feedback: We actively collect customer feedback to drive continuous improvement in product quality.

The following outlines a typical production process for Mulberry Leaf Extract, incorporating various extraction techniques and steps to ensure efficient preparation and stringent quality control:
1. Raw Material Preparation
Mulberry Leaf Collection and Processing: Premium mulberry leaves are selected as the raw material, typically using dried leaves. The leaves are washed, air-dried, and then pulverized, passing through a sieve (e.g., 60 mesh) to obtain mulberry leaf powder.
Raw Material Pretreatment: Some processes involve degreasing the mulberry leaf powder with solvents such as petroleum ether to remove impurities and enhance subsequent extraction efficiency.

2. Extraction Process
Water Extraction: Mulberry leaf powder is mixed with 10-20 times its weight in water, heated to 35-45°C, and subjected to ultrasonic-assisted extraction for 45-90 minutes to improve extraction efficiency. The resulting aqueous extract is then filtered.
Alcohol Extraction: Mulberry leaf powder is soaked in alcohol and extracted using heat reflux, yielding an alcoholic extract.
Ultrasonic-Assisted Extraction: Ultrasonic technology is employed during the extraction process to effectively enhance extraction efficiency and the content of active ingredients.

3. Refinement Process
Flocculation and Sedimentation: The aqueous extract's pH is adjusted to 3-4, a flocculant is added, and the mixture is stirred and allowed to settle for 20-30 minutes to precipitate impurities.
Filtration and Clarification: Techniques such as microfiltration and ultrafiltration are used to remove suspended solids and macromolecular impurities from the extract, resulting in a clarified solution.
Concentration: Thin-film evaporation or vacuum evaporation is employed to concentrate the extract to the desired level.
Purification: Column chromatography and other methods are used to further purify the active components, such as 1-Deoxynojirimycin (DNJ).

4. Drying and Packaging
Spray Drying: The concentrated extract is processed into powder using spray drying technology.
Vacuum Freeze-Drying: For products requiring the preservation of more active ingredients, vacuum freeze-drying is utilized.
Packaging: The dried mulberry extract undergoes final testing and is then packaged. Various packaging specifications are available, including small packages (e.g., 1kg/bag), medium packages (e.g., 25kg/cardboard drum), and large packages (e.g., 50kg/cardboard drum).

5. Quality Control Test
Testing: Rigorous testing is performed on raw materials, intermediates, and finished products throughout the production process, including analysis of ingredient content (e.g., DNJ, flavonoids), heavy metals, and pesticide residues.
Quality Standards: Products are ensured to meet international quality standards, such as ISO and GMP.

Jiuyuan Biological places a high priority on scientific research, collaborating with numerous renowned research institutions and universities both domestically and internationally to investigate the efficacy of Mulberry Leaf Extract. Our products have undergone multiple clinical trials and scientific validations, demonstrating significant effects in areas such as blood glucose regulation, lipid modulation, antioxidant activity, and anti-inflammatory properties.

Blood Glucose Regulation: In a 12-week clinical trial involving 100 diabetic patients, daily consumption of 500mg Mulberry Extract (containing 10% DNJ) resulted in an average 20% reduction in postprandial blood glucose levels and a 15% reduction in fasting blood glucose levels.
Lipid Modulation: Another 8-week study involving 80 patients with hyperlipidemia showed that daily consumption of 300mg Mulberry Extract (containing 10% flavonoids) led to an average 18% decrease in total cholesterol (TC) levels, a 22% decrease in low-density lipoprotein cholesterol (LDL-C) levels, and a 10% increase in high-density lipoprotein cholesterol (HDL-C) levels.
Antioxidant Activity: The flavonoid compounds present in the Leaf Extract exhibit potent antioxidant capabilities. In in vitro experiments, the antioxidant activity of the Extract was shown to be three times greater than that of vitamin C, effectively scavenging free radicals and mitigating oxidative stress.
Anti-inflammatory Effects: The flavonoid components have demonstrated the ability to inhibit the production of inflammatory mediators, thereby reducing inflammatory responses. In animal studies, this Extract significantly reduced inflammatory cytokine levels in induced inflammation models, achieving an inhibition rate of 40%.

DNJ Inhibition of α-glucosidase: 1-Deoxynojirimycin (DNJ), a key component of the Extract, acts as a natural α-glucosidase inhibitor. By binding to α-glucosidase, it prevents the enzyme from breaking down disaccharides (e.g., sucrose, maltose), thereby delaying glucose absorption and attenuating postprandial glucose spikes.
Antioxidant and Anti-inflammatory Effects of Flavonoids: The flavonoid compounds in this Extract, such as rutin and quercetin, possess strong antioxidant properties. They effectively neutralize free radicals, reduce oxidative stress, and protect cell membrane integrity. Additionally, these flavonoids inhibit the production of inflammatory cytokines, contributing to their anti-inflammatory effects.

1. Pharmaceutical Field

Diabetes Treatment: Mulberry Leaf Extract is widely used in the adjunctive treatment of diabetes. Its hypoglycemic effects make it a crucial natural pharmaceutical ingredient.

Hyperlipidemia Treatment: It can be used as an adjunct therapy for patients with hyperlipidemia, helping to regulate lipid levels.

Cardiovascular Disease Prevention: The lipid-lowering, antioxidant, and antihypertensive effects make it valuable in the prevention and adjunctive treatment of cardiovascular diseases.

Anti-inflammatory Drugs: The flavonoid components in Mulberry Leaf can be utilized in the development of anti-inflammatory drugs.

Antibacterial Drugs: The antibacterial properties of Mulberry Leaf present potential applications in the development of antibacterial drugs.

Immunomodulators: It can be used to develop immunomodulators, enhancing the body's immune function.

2. Food Field

Functional Food Additives: It is incorporated into various functional foods, such as health supplements, beverages, and biscuits, to regulate blood glucose and lipid levels, and enhance immunity.

Weight Loss Foods: The weight loss effects make it a key ingredient in weight loss foods.

Nutritional Supplements: Rich in various vitamins and amino acids, it can serve as a nutritional supplement.

3. Cosmetic Field

Antioxidant Products: The flavonoid components in Mulberry Leaf, with their antioxidant properties, can be used in the development of antioxidant cosmetics.

Anti-inflammatory Products: The anti-inflammatory effects of Mulberry Leaf also find applications in anti-inflammatory cosmetics.

4. Animal Husbandry Field

Animal Feed Additives: It can be added to animal feed to regulate blood glucose and lipid levels, and promote intestinal health in animals.

Due to its diverse benefits and broad application prospects, Mulberry Leaf Extract is receiving increasing attention and research.

We recognize that each client's needs are unique, and therefore, we offer highly customized Mulberry Extract products. Whether it's specific component concentrations (e.g., DNJ content 1%-10%, flavonoid content 5%-8%), product specifications (e.g., powder, granules, liquid), or specific application requirements, we can tailor our products to meet your exact specifications.
 

Powder Specifications: We offer powders with varying particle sizes to suit diverse application scenarios, including 80 mesh, 100 mesh, and 120 mesh.
Liquid Extracts: We provide liquid extracts at various concentrations, ranging from 10% to 50%.
Packaging Options: We offer a variety of packaging specifications, including small packages (1kg/bag, 5kg/bag), medium packages (25kg/cardboard drum), and large packages (50kg/cardboard drum). We also provide customized packaging services upon client request.

Our dedicated research and development team provides comprehensive technical support and formulation recommendations. Our experts can offer scientific formulation design and application guidance based on your product requirements, helping you develop more competitive products.

Jiuyuan Biological boasts robust production capabilities and a reliable supply chain. Our production facilities are equipped with advanced machinery and adhere to strict quality control procedures, guaranteeing consistent and stable large-scale production. We have established long-term partnerships with reputable suppliers to ensure a steady supply of raw materials.

We offer a wide range of flexible packaging options to accommodate diverse client needs. Whether it's small-batch sample packaging or large-volume cardboard drum packaging, we provide customized packaging services. Additionally, we collaborate with numerous international logistics companies to ensure secure and timely product delivery.

We provide all necessary documentation for our products, including:
COA (Certificate of Analysis): Detailing the product's composition, purity, active ingredient content, and other information.
MSDS (Material Safety Data Sheet): Providing product safety information, including toxicity, hazards, first aid measures, etc.
Organic Certification Documents: Such as USDA Organic and EU Organic certification certificates.
Other Compliance Documents: Such as GMP, ISO 9001, ISO 22000, and FSSC 22000 certification documents.
These documents ensure product compliance and quality reliability, helping buyers use and sell our Organic Bupleurum Root Extract with confidence.

Contact us via elsa.marketing@jiuybiotech.com.

We have established a comprehensive after-sales service system to promptly address customer feedback and issues.
We will actively respond to any customer inquiries or dissatisfaction and provide solutions.
We consistently aim for customer satisfaction and continuously improve our service quality.
In summary, Shaanxi Jiuyuan Biotechnology not only provides high-quality organic Angelica extract but also comprehensive professional services and support. We are committed to building long-term and stable partnerships with our customers for mutual development.

We cooperate with multiple professional logistics companies to provide efficient and secure logistics services.
We ensure timely and complete delivery of products to customers, regardless of their location.
We offer a variety of logistics options for customers to choose from, including express delivery, air freight, and sea freight.

Storage: Keep in a cool, dry, and clean place, protect from moisture and direct light.
Bulk Package: 25kg/drum.
Lead Time: 7 days after your order.
Shelf Life: 2 years.
Remark: Customized specifications also can be achieved.

Factory Scale:
Shaanxi Jiuyuan Biotechnology Co., Ltd.'s factory covers an area of over 70,000 square meters.
It features 6 production workshops and 10 production lines, with an annual production capacity of over 6,000 tons.
The factory is equipped with a 1,000-square-meter Class 100,000 clean workshop and multiple sets of automated equipment.

We precisely position the application areas of our Mulberry Leaf Extract based on the unique demands of various markets.
Asian Markets: In Asia, there is a strong demand for Mulberry Extract in traditional medicine and health supplements. Our products, with their proven efficacy in blood glucose regulation, lipid modulation, and immune enhancement, are highly trusted by consumers.
European and American Markets: In Europe and America, the functional food and nutritional supplement markets are experiencing rapid growth. Our Mulberry Extract, backed by scientific validation and high-quality standards, is the preferred raw material for numerous brands.

According to the latest market research reports, the global Mulberry Leaf Extract market is on a rapid growth trajectory. As consumers increasingly prioritize health and natural products, Mulberry Extract holds significant potential in functional foods, nutritional supplements, cosmetics, and other applications.
Market Competitive Advantages: Jiuyuan Biological Co., Ltd. holds a prominent position in the global Mulberry Extract market, driven by our superior product quality, innovative application development capabilities, and robust supply chain. Our products not only meet international quality standards but also offer competitive pricing, providing clients with cost-effective solutions.

Shaanxi Jiuyuan Biological Co., Ltd. actively participates in international industry trade fairs to showcase our products and technologies, and to engage directly with potential buyers. We have recently participated in the following exhibitions:
Vitafoods Europe: Europe's largest nutraceutical trade fair, attracting industry experts and brands from around the world. We showcased the diverse applications of our Mulberry Extract and established cooperation intentions with several leading international companies.
SupplySide West: The largest nutritional supplement trade show in the United States, serving as an industry trendsetter. We presented our latest research findings and product innovations, attracting significant customer attention.
CPhI Worldwide: A global pharmaceutical industry trade show covering the entire supply chain from raw materials to finished products. We highlighted the application potential of Mulberry Extract in the pharmaceutical sector and forged partnerships with numerous pharmaceutical companies.

By participating in these exhibitions, we not only demonstrated our company's strength and product advantages but also established extensive connections with global clients, further expanding our overseas markets.

We sincerely invite you to collaborate with Jiuyuan Biological. to explore the boundless potential of Mulberry Leaf Extract in the global market. We are confident that our professional expertise and premium services will deliver long-term, stable cooperative value.
Please do not hesitate to contact us if you have any further questions or requirements.

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