Gynostemma Pentaphyllum Leaf Extract

Gynostemma Pentaphyllum Leaf Extract is a high-purity herbal extract derived from the Gynostemma pentaphyllum plant, a traditional medicinal herb highly valued in Asia for its adaptogenic and wellness-supporting properties. Rich in gypenosides, flavonoids, and polysaccharides, it is known for supporting cardiovascular health, immune regulation, metabolic balance, and anti-fatigue effects.

Unlike generic Gynostemma extracts, our product leverages ultra-fine pulverization, combined hydro-alcoholic extraction, and precision purification to ensure consistently high gypenoside content, optimized bioavailability, and superior clarity. Available as powders, capsules, and teas, it caters to a diverse range of industrial and consumer applications.

CAS Number: 15588-68-8
Appearance: Light yellow to brown fine powder
Molecular Formula: C80H126O44
Molecular Weight: 1791.83

Learn more about our company: Jiuyuan Biotech Company Profile
Explore more plant extracts: Standard Plant Extract Collection

Jiuyuan Gynostemma Extract delivers up to 98% gypenosides with verified immune-boosting and lipid-regulating benefits.

1. Raw Material Selection:
We cultivate and source Gynostemma from the pristine Qinling Mountains, ensuring clean, pesticide-free herbs. Only carefully screened stems and leaves enter production.

2. Advanced Extraction Process:

• Hydro-Alcoholic Extraction: Combines water and ethanol (60–80%) to maximize gypenoside yield.
• Microwave-Assisted Extraction: Reduces degradation of active compounds while increasing efficiency.
• Purification: HP20 macroporous resin column chromatography or petroleum ether extraction ensures >98% gypenoside purity.

3. Drying & Pulverization:
Spray drying or vacuum drying creates a fine, uniform powder with particle size customizable from 80 to 350 mesh.

4. Full Quality Control:

• HPLC-based testing confirms gypenoside content.
• Heavy metals, pesticide residues, and microbial levels are strictly monitored.
• Every batch includes COA, MSDS, and compliance documentation.

Jiuyuan's GMP-standard extraction guarantees consistent, high-purity Gynostemma powder with complete traceability.

1. Functional Foods & Beverages:

Gynostemma tea, oral liquids, beverage formulations, and nutritionally enhanced foods.

Differentiator: natural adaptogenic sweetness with verified bioactive compound retention.

2. Pharmaceuticals & Supplements:

Supports cardiovascular health, metabolic regulation, anti-fatigue, and adjunctive cancer care.

Differentiator: High-standard, lab-verified gypenoside concentrations that meet international pharmacopeia levels.

3. Cosmetics & Personal Care:

Skincare: anti-aging, moisturizing, antioxidant protection.

Haircare: improves elasticity, density, and hair strength.

Differentiator: Full-spectrum flavonoids and polysaccharides enhance skin and hair bioactivity.

4. Dietary Supplements:

Immune regulation, stress reduction, enhanced energy, and anti-fatigue benefits.

Differentiator: Consistent batch quality ensures reliable functional claims for global markets.

• Premium Raw Materials: Exclusive cultivation in the Qinling Mountains ensures high-quality herb with optimal phytochemical profile.
• GMP & ISO-Compliant Production: Entire production chain from raw material to finished powder adheres to global quality standards.
• Advanced Extraction Technology: Combines water, ethanol, and microwave-assisted processes for maximal bioactive retention.
• Full Traceability & Third-Party Testing: Each batch comes with COA and testing from accredited laboratories, supporting YMYL compliance.
• Scalable Supply: Annual capacity of 1,000 tons with customizable specifications and packaging for industrial clients.

Jiuyuan delivers high-purity, traceable Gynostemma extract, ensuring reproducible adaptogenic and health benefits across industries.

COA: Detailed composition and active content verification

MSDS: Safety and handling data

Organic Certificates: USDA Organic, EU Organic

Quality Certifications: GMP, ISO9001, ISO22000, FSSC22000, HACCP, HALAL, KOSHER

Jiuyuan Biotech – Your Trusted Partner for Premium Herbal Extracts
With over 13 years of extraction expertise, 6 production workshops, and 10 advanced production lines, Jiuyuan ensures consistent quality, reliable supply, and regulatory-compliant herbal extracts for global markets.

Jiuyuan combines advanced technology, GMP compliance, and traceable sourcing to deliver premium Gynostemma extracts for food, pharma, and personal care industries.

We implement a comprehensive quality control system, scientifically managing every production stage of our Plant Extract Products. Rigorous adherence to operational standards and full traceability of each batch ensures product reliability. We have earned numerous domestic and international certifications, including SC Food Production License, ISO9001, ISO22000, Health Food Raw Material Production License, HACCP, Kosher, and Halal, demonstrating our commitment to exceeding industry standards.

Storage: Keep in a cool, dry, and clean place, protect from moisture and direct light.
Bulk Package: 25kg/drum.
Lead Time: 7 days after your order.
Shelf Life: 2 years.
Remark: Customized specifications can be achieved.

References

1. Takemoto et al. investigated the cardiovascular protective effects of Gynostemma pentaphyllum, demonstrating that its aqueous extract and gypenosides can protect against coronary spasm and arrhythmias in experimental models, indicating potential cardiovascular benefits. PubMed
2. A chemical and biological study of gypenosides from Gynostemma pentaphyllum showed anti‑inflammatory activity through inhibition of proinflammatory mediators including IL‑6, IL‑1β, COX‑2 and TNF‑α in macrophage cells, supporting its role in modulating immune response and inflammation. PubMed
3. Recent pharmacological research identified that gypenosides exert cardioprotective effects by promoting mitophagy and activating key cellular signaling pathways (PI3K/Akt/GSK‑3β/Mcl‑1), suggesting mechanisms for cardiometabolic support. PubMed
4. A randomized controlled trial systematic review examining Gynostemma pentaphyllum found evidence for its effects on lipid profiles in dyslipidemia patients, providing clinical‑level support for cardiovascular and metabolic health benefits. PubMed