Genistein Powder
CAS Number: 446-72-0
Molecular Formula: C15H10O5
Molecular Weight: 70.2369
Specification: 98% min by HPLC
Quality Standard: Enterprise Standard
Appearance: Off-white to pale yellow powder
Packaging: 25kg/drum
Storage Conditions: Store in a cool, dry, and dark place, sealed.
Part Used: Flower buds
Dye wood material: natural origin, possesses multiple activities
Genistein Nutrition and Health
Genistein Powder, also known as genistein, is an isoflavone compound derived from plants. It was first isolated in 1899 from a plant in the genus *Genista tinctoria* (commonly known as genistein), hence its name. It is a typical phytoestrogen, exhibiting estrogen-like activity due to its structural similarity to the mammalian estrogen 17-β-estradiol. It can bind to estrogen receptors α and β, producing estrogen-like or antagonistic effects. Its diverse mechanisms of action and potential health benefits have made it one of the most sought-after natural active ingredients in the functional food and dietary supplement industry.
Genistein: Naturally derived, with multiple activities
Genistein, as a natural component with multiple activities, has broad application prospects in the field of nutrition and health.
Mechanism of action
1. 🥇 Oxidative stress balance
In animal studies, genistein supplementation can increase the activity of antioxidant enzymes (such as superoxide dismutase SOD and catalase) and reduce the levels of oxidative stress markers (such as malondialdehyde MDA), thereby mitigating free radical damage to tissues.
2. 🧊 Estrogen-like effects
Studies in estrogen receptor-expressing cells and animal models have shown that genistein can act as a phytoestrogen, binding to ERα/ERβ to exert a bidirectional estrogen-like regulatory effect, improving postmenopausal physiological disorders and maintaining hormonal balance in the body.
Certificate of Analysis
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Item |
Specification |
Result |
Method |
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Basic Product Information |
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| Botanical Source | Flowering buds of Sophora japonica L |
Conforms |
/ |
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Part of the Plant |
Bud |
Conforms |
/ |
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Marker Compounds |
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Assay |
>98% |
Conforms |
HPLC |
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Organoleptic Data |
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Appearance |
Fine Powder |
Conforms |
Sensory |
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Color |
Off-white to pale yellow powder |
Conforms |
Sensory |
|
Odor |
Characteristic |
Conforms |
Sensory |
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Process Data |
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Method of Processing |
Extraction and concentration |
/ |
/ |
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Drying Method |
Spraying drying |
/ |
/ |
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Physical Characteristics |
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Particle Size |
100% pass 80 mesh |
100% pass |
AOAC973.03 |
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Moisture |
≤5.0% |
3.7% |
GB/T5009.3 |
|
Ash Content |
≤5.0% |
3.1% |
CP2010 |
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Heavy Metals |
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Total Heavy Metals |
<10ppm Max. |
Conforms |
GB 5009.74 |
|
As |
≤1.0 ppm |
0. 11ppm |
GB/T5009. 11 |
|
Pb |
≤0.5 ppm |
0.31ppm |
GB/T5009. 12 |
|
Cd |
≤0.5 ppm |
0. 12ppm |
GB/T5009. 15 |
|
Hg |
≤0.05 ppm |
0.012ppm |
GB/T5009. 17 |
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Microbiology |
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Total Plate Count |
≤10000 cfu/g |
1800cfu/g |
GB/T4789.2 |
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Total Yeast & Mold |
≤200 cfu/g |
40cfu/g |
GB/T4789. 15 |
|
E.Coli |
Negative/ 10g |
Negative/ 10g |
SN0169 |
|
Salmonella |
Negative/ 10g |
Negative/ 10g |
GB/T4789.4 |
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Shelf Life |
24 months under the conditions above and in its original packaging. |
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Storage |
Store in a cool & dry place, keep away from strong light and heat. |
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certifications
At JIUYUAN BIOTECH, product quality is our top priority. We achieve this through a comprehensive and robust quality control system that meticulously manages every stage of production with scientific rigor. By strictly adhering to operational protocols, we ensure the traceability of every batch of our products.
Shaanxi Jiuyuan Bio currently holds numerous domestic and international industry certifications and qualifications, ensuring our operations in production, R&D, and sales consistently meet demanding standards. Our key certifications include:

With our advanced production facilities, a state-of-the-art testing and control center, and our complete quality control system, we consistently ensure the safety and stability of our products and services.
Choose Jiuyuan Biotech: Your Trustworthy Partner
Our self-owned facility with an annual capacity of 6,000 tons, combined with the newly added Pilot Scale Flexible Production Line, means:
- Quality Consistency: Large-scale capacity guarantees stable supply and consistent batch quality.
- Lower MOQ: Small-batch orders under 500kg can be easily fulfilled, supporting your rapid new product testing and market introduction.
- Full Process Traceability: Strict control over every step from the organic farm to your warehouse, ensuring a transparent and reliable supply chain.
📩 Contact us now to request a sample of Organic Hawthorn Powder and discuss your customized solution!
Product Application
Nutritional supplements: Hormone-balancing supplements and complex formulas for women
Functional foods: Allergen-free meal replacements, functional foods
Production Process
Raw Material Cleaning (Organic Hawthorn Fruit) → Pitting and Crushing → Low-Temperature 45°C Vacuum Drying → Ultra-Fine Pulverization and Sieving → Sterilization and Packaging.

Clinical research
In a study of psoriasis patients, daily supplementation with 75 mg or 150 mg of genistein for 8 weeks showed no significant improvement in clinical skin lesion scores in healthy controls. However, changes in oxidative stress and inflammatory markers were observed: the expression of genes related to inflammation and oxidation, such as IL8, IL6, and NFKB1, was suppressed in peripheral blood mononuclear cells and skin lesion tissue.
In a 2-year randomized, double-blind, placebo-controlled clinical trial in postmenopausal women, genistein significantly improved menopausal hot flashes and increased the vaginal epithelial maturation index through estrogen-like effects, and no adverse effects of endometrial hyperplasia or thickening were observed with long-term intervention.
In a randomized clinical trial in postmenopausal women with osteoporosis, the phytoestrogen genistein was shown to regulate bone metabolism balance, improve bone mineral density, and protect against postmenopausal bone loss through the detection of bone metabolism markers, bone mineral density, and safety indicators, with good safety profile.

Why Choose jiuyuan
Company Profile
Founded: 2012, based in Xi'an at the northern foot of the Qinling Mountains.
Business Scope: A high-tech enterprise specializing in the R&D, production, and sales of plant extracts and fruit and vegetable powders.
Mission: Committed to providing high-quality products and services to the health food, food, and cosmetics industries, to lead China's plant extract sector.

Core Strengths
R&D and Quality Control:
Equipped with advanced testing equipment, including HPLC and UV spectrometers, for precise analysis of active ingredient content and purity.
A professional testing team provides detailed product analysis reports to ensure quality and safety.
Supply Chain Management:
Maintains long-term, stable partnerships with local farmers.
Utilizes a contract farming and procurement model to guarantee a consistent supply of high-quality raw materials.
Production and Warehousing:
Boasts comprehensive production facilities with advanced equipment and automated lines to meet large-volume demands.
Our robust warehousing system ensures optimal storage conditions, maintaining product quality and stability.
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Delivery Methods, Packages And Storage
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Express Under 100kg, 3-5Days Door-to-door service easy to pick up the goods |
By Sea Over300kg, Around 30 Days Port-to-port service professional clearance broker needed |
By Air 100kg-1000kg, 5-7Days Airport-to-airport service professional clearance broker needed |
Packages :

where to buy
To inquire or request a sample, contact info@jiuybiotech.com Our team is ready to help you with specifications, pricing, or customs documentation. Trust Shaanxi Jiuyuan Biotech as your supplier and move from curiosity to confidence with a clear supply and documentation promise.
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