Lion's Mane Mushroom Extract Powder

Lion's mane mushroom extract powder derived from the fruiting body of Hericium erinaceus is a categorically different ingredient from mycelium-on-grain powder. The fruiting body is where hericenones - the diterpenoid compounds unique to H. erinaceus that stimulate nerve growth factor (NGF) synthesis - are found in meaningful concentrations. Erinacines, the cyathane-type diterpenoids with documented NGF-inducing activity, are present in the mycelium but require verified mycelium-only biomass, not a grain-diluted composite. A supplier who cannot confirm whether their product is fruiting body, pure mycelium, or mycelium-on-grain cannot tell you what is actually in the bag.

At Jiuyuan Biotech, our organic lion's mane extract is produced exclusively from the fruiting bodies of Hericium erinaceus cultivated on natural, chemical-free substrates under controlled conditions (22–28°C, 80–90% humidity) that closely replicate the mushroom's native temperate forest environment. Polysaccharides are concentrated using low-temperature water extraction and alcohol precipitation, standardized to 10–50% content with a documented 40%+ increase in bioavailability versus raw powder. Every batch is dual-certified USDA NOP and EU Organic, and ships with a batch-specific COA disclosing assay method and reference standard.

Standard Organic Lion's Mane Extract - Hot Water Extraction

Premium Grade - Dual Extraction (Water + Ethanol)

Available Specification Range

Custom specifications available: specific beta-glucan-to-polysaccharide ratios, HPLC-verified hericenone content, 100–200 mesh particle sizes, and water-soluble encapsulated formats. Contact us with your target specification.

Polysaccharides & β-Glucans

• Range: 10%–50%
• Function: immune modulation, gut microbiota interaction
• Application: immune capsules, gut-health beverages

Hericenones & Erinacines

• Total ≥ 0.7%
• Function: associated with nerve growth factor (NGF) synthesis
• Application: cognitive support, nootropic formulations

Lion's mane mushroom extract powder occupies a unique position in the functional ingredient market - it is the only widely available botanical ingredient with documented NGF-stimulating compounds, placing it at the intersection of cognitive health, immune support, and gut-brain axis nutrition.

Recommended Usage Rates:

• Capsules / Tablets: 250–1,000 mg per serving (extract grade)
• Beverages: 0.1–0.5% w/v
• Food applications: 0.2–1.0% w/w
• Nootropic stack blends: 300–500 mg per serving (standardized extract)

Each batch tested for:

• Active compounds (HPLC)
• Heavy metals (ICP-MS)
• Microbiology (USP standards)
• Residual solvents

Typical Results:

• Pb: <0.1 ppm
• Total Plate Count: <300 cfu/g
• Yeast & Mold: <50 cfu/g
• Pathogens: Negative

Full COA available upon request.

Our commitment to quality is validated by a comprehensive suite of international certifications, ensuring our products meet the highest global standards.

• USDA Organic (US-2025-06-013) & EU Organic (ES-ECO-037-18588): These dual certifications are critical for market access and consumer trust in the US and Europe. They guarantee that our products are grown and processed without synthetic pesticides, fertilizers, or GMOs, appealing to health-conscious consumers and meeting strict regulatory requirements.
• cGMP: Current Good Manufacturing Practices (cGMP) ensure that our products are consistently produced and controlled according to quality standards. This certification is essential for dietary supplement and food manufacturers, proving our commitment to safety and efficacy.
• HACCP: The Hazard Analysis and Critical Control Point (HACCP) system is a preventative approach to food safety. It identifies and manages potential hazards throughout the production process, providing an extra layer of assurance for product safety.
• FSSC 22000 & ISO 22000: These certifications demonstrate a robust food safety management system. FSSC 22000 is a globally recognized standard, and ISO 22000 provides a framework for managing food safety risks, ensuring our products are safe for consumption worldwide.
• Non-GMO Project Verified #C0025891: This is North America's most trusted third-party verification for non-GMO products. It provides consumers with confidence that our ingredients have been independently verified to avoid genetic engineering.
• ISO 9001:2015: This globally recognized quality management system standard confirms our dedication to continuous improvement, customer satisfaction, and operational efficiency.
• Halal & Kosher (Shaanxi Halal Association & SKS Kosher): These certifications confirm that our products meet the dietary and preparation requirements of Islamic and Jewish law, respectively. They open up vast market opportunities and provide assurance to specific consumer groups.

• With over 10 years of experience specializing in mushroom extracts, we have exported to more than 60 countries with zero customs detentions.
• Large-Scale Facility: Our 70,000 square meter production plant features six workshops and 10 production lines, with an impressive annual capacity of over 6,000 metric tons.
• Advanced Infrastructure: We operate two Class 100,000 clean rooms and a 500 square meter R&D and testing center to ensure product purity and quality.
• Expert Team: Our 20-person professional R&D team is dedicated to innovation and technical excellence, ensuring our products remain at the forefront of the industry.

Storage: Keep in a cool, dry, and clean place, protected from moisture and direct light.
Bulk Package: 25kg/drum.
Lead Time:  Within 7 days after your order.
Shelf Life: 2 years.
Remark: Customized specifications can also be achieved.

Q1: How do I know your Lion's Mane Mushroom Extract Powder is genuinely fruiting body and not mycelium-on-grain?

Every incoming fruiting body lot undergoes a starch contamination test (iodine colorimetric method) before processing begins. A starch-positive result triggers rejection. Our finished product COA reports starch content as "not detected," which is the definitive confirmation of fruiting body source. We also perform TLC species identity fingerprinting on every incoming lot. Buyers are welcome to commission independent starch testing and enzymatic beta-glucan assay on our samples before placing any commercial order - we actively support this.

Q2: What is the difference between polysaccharide content and beta-glucan content, and which one should I specify?

Total polysaccharide content (measured by UV spectrophotometry, phenol-sulfuric acid method) includes all polysaccharide fractions - both fungal beta-glucans and alpha-glucans (starch). In a pure fruiting body extract with no grain contamination, total polysaccharides and beta-glucans will be closely correlated. In a mycelium-on-grain product, total polysaccharides will be significantly higher than beta-glucans because starch inflates the UV reading. For a premium supplement with a cognitive or immune support claim, specify beta-glucan content (enzymatic assay, Megazyme method) - not just total polysaccharides. We report both on our COA.

Q3: Does your extract contain hericenones, and can you quantify them?

Yes. Our fruiting body extract contains hericenones - the diterpenoid compounds unique to H. erinaceus fruiting bodies that stimulate NGF synthesis. For our standard hot water extraction grade, hericenones are present but not routinely quantified (they are alcohol-soluble and partially lost in water-only extraction). For our premium dual-extraction grade (water + ethanol), hericenone content is higher and HPLC quantification is available on request. If your formulation requires a declared hericenone content for label claims, specify the dual-extraction grade.

Q4: Can I use your organic lion's mane extract to make NGF-support claims on my finished product?

This depends on your target market's regulatory framework. In the US, structure/function claims such as "supports healthy nerve function" or "supports cognitive health" are permissible for dietary supplements under 21 CFR 101.93, provided the claim is truthful, not misleading, and substantiated. The published clinical research on H. erinaceus fruiting body extract (including Mori et al., 2009, Phytotherapy Research) provides substantiation for cognitive health positioning. We recommend working with your regulatory counsel to finalize specific claim language for your target market.

Q5: What extraction method produces the most complete bioactive profile?

Dual extraction - combining hot water extraction (for polysaccharides and beta-glucans) with ethanol extraction (for hericenones and other alcohol-soluble diterpenoids) - produces the most complete bioactive profile. Hot water extraction alone captures the polysaccharide fraction but leaves most hericenones behind. For a nootropic formula where both immune support (beta-glucans) and cognitive positioning (hericenones) are relevant, the dual-extraction grade is the appropriate choice. For applications where only immune support or general wellness positioning is required, the hot water extraction grade is adequate and more cost-effective.

Q6: Is your organic lion's mane extract non-irradiated?

Yes. Our organic mushroom extracts are not irradiated. Irradiation is incompatible with organic certification under both USDA NOP and EU Organic regulations - NOP explicitly prohibits ionizing radiation as a post-harvest treatment for certified organic products. Our HTST sterilization protocol (135–150°C for 2–8 seconds) provides the required microbiological safety without irradiation.

Q7: What documentation do you provide for EU and US market compliance?

Our standard documentation package includes: batch-specific COA (with polysaccharide, beta-glucan, starch, heavy metals, pesticide residue, and microbiology results), organic transaction certificate (TC), TDS, MSDS/SDS, allergen declaration, GMO-free statement, BSE/TSE-free statement, species identity TLC fingerprint, and copies of all active certifications (USDA Organic, EU Organic, FDA registration, cGMP, FSSC 22000, Halal, Kosher). For EU Novel Food compliance documentation or US NDI dossier support, contact us directly.

Q8: Can you supply a custom lion's mane extract with a specific beta-glucan-to-hericenone ratio?

Yes. Our R&D and extraction team supports custom specification development. We can adjust extraction solvent ratios, concentration parameters, and drying protocols to hit a defined beta-glucan content, hericenone content, or both simultaneously. Custom grades are produced using NOP and EU Organic-compliant inputs and processing aids, and are covered under our existing organic certifications. Minimum order quantities and development timelines vary by specification complexity. Contact us at info@jiuybiotech.com to initiate a technical discussion.

The cognitive health supplement market is growing fast - and the lion's mane category is growing with it. But it is also a category where sourcing shortcuts are endemic: mycelium-on-grain passed off as fruiting body, starch-inflated polysaccharide numbers, and organic certificates that don't survive a compliance audit.

Lion's mane mushroom extract powder from Jiuyuan Biotech is produced from verified Hericium erinaceus fruiting bodies, cultivated on natural substrates under controlled conditions, extracted using low-temperature water extraction and alcohol precipitation for maximum bioavailability, and dual-certified USDA NOP and EU Organic. Every batch ships with a starch-negative test result, a beta-glucan content verified by enzymatic assay, and a lot-specific organic transaction certificate.

Our facility is FDA-registered, cGMP-certified, and FSSC 22000-audited. Samples are available from 10g. MOQ starts at 1 kg.

📧 Contact us: info@jiuybiotech.com 📞 Phone: +86 029 88215052 🌐 Website: www.jiuyuanbio.com

Send us your target specification - beta-glucan content, hericenone requirement, organic certification, and annual volume - and we'll respond with a sample offer, full technical dossier, and competitive pricing within 24 hours.