Cordyceps Mycelium Extract

Cordyceps mycelium extract is a natural dietary supplement derived from the cultivated mycelium of the Cordyceps militaris fungus. Through a carefully controlled extraction process, we capture the potent bioactive compounds found in this medicinal mushroom, including polysaccharides, nucleosides(like cordycepin and adenosine), and vitamins. These compounds have been shown to support immune function, reduce oxidative stress, and promote overall well-being. Our extract undergoes rigorous quality control measures to ensure purity and consistency, making it a reliable choice for manufacturers of dietary supplements, functional foods, and nutraceuticals. The extract's safety and stability have been confirmed through extensive testing, making it a trusted ingredient in the health and wellness industry.

(1) Large-Scale Production Capacity: With a production area of 70,000 square meters, we are equipped to handle large-scale orders, ensuring a continuous and stable supply chain.

(2) Consistent Product Quality: Cordycepic acid content is a key indicator of Cordyceps quality. By precisely controlling cultivation conditions, we ensure consistent product quality across all batches.

(3) Diverse Product Specifications: We offer a wide range of Cordyceps mycelium extract specifications to meet the diverse needs of our customers. This includes varying levels of polysaccharides, cordycepin, cordycepic acid, and adenosine.

Polysaccharide: 5%, 10%, 30%, 50% (UV)

Cordycepin: 1%, 3%, 5%, 10%, 20%, 98% (HPLC)

Cordycepic Acid: 5%, 10% (HPLC)

Adenosine: 5%, 7%, 10% (HPLC)

(4) Advanced Extraction Technology: We employ cutting-edge extraction techniques such as enzymatic fermentation, ultrasonic-assisted extraction, and microwave-assisted extraction. These methods enhance extraction efficiency, reduce impurities, and ensure the purity and activity of the extract.

Cordyceps mycelium extract offers a wide range of health benefits, primarily attributed to its unique bioactive compounds. These benefits include:

Immunomodulation: Enhances immune function by increasing natural killer (NK) cell activity, lymphocyte proliferation, and the production of type 1 helper T cell cytokines.

Anti-tumor activity: Cordycepin and polysaccharides exhibit potent anti-proliferative effects on various cancer cell lines, including MCF-7, Hep-G2, and Hela cells.

Anti-fatigue and enhanced athletic performance: Delays fatigue onset, increases maximal oxygen consumption, and improves tolerance to high-intensity exercise.

Antioxidant properties: Scavenges free radicals, enhances reducing power, and chelates ferrous ions. It also upregulates the activity of superoxide dismutase (SOD) and glutathione peroxidase, demonstrating strong antioxidant capacity.

Anti-inflammatory effects: Reduces the production of pro-inflammatory cytokines such as interleukin-6 and tumor necrosis factor-α.

Blood glucose control: Enhances glucose utilization in skeletal muscle, improves insulin sensitivity, and stimulates insulin release, leading to decreased fasting blood glucose levels.

Thrombolytic activity: Possesses fibrinolytic enzyme activity, binding to fibrin and activating the fibrinolytic pathway, thereby preventing thrombosis.

Neuroprotective effects: Protects neurons by reducing infarct size, mitigating brain edema, and limiting blood-brain barrier damage, likely related to the anti-inflammatory activity of cordycepin.

Hepatoprotective effects: Reduces liver cell damage, associated with its antioxidant and lipid-lowering properties.

Nephroprotective effects: Inhibits low-density lipoprotein-induced glomerular cell hypertrophy and limits mesangial cell proliferation, demonstrating renal protective effects.

Safety: Demonstrates a favorable safety profile in animal studies, with no observed toxic effects at high doses. Human studies have not reported any serious adverse events.

Cordyceps mycelium extract has found widespread application in various industries due to its numerous health benefits. Key applications include:

 

 

01

Dietary Supplements

Owing to its anti-tumor, immunomodulatory, and anti-aging properties, Cordyceps has been extensively used in the development of dietary supplements. 

 

02

Functional Foods

Cordyceps has been incorporated into a variety of functional foods, such as Cordyceps beverages, Cordyceps polysaccharide yogurt, and Cordyceps effervescent tablets.

 

03

Pharmaceuticals

Producing or checking existing products according to your customised order and dispatching the products

 

04

Cosmetics

The antioxidant properties of Cordyceps polysaccharides and cordycepin have made them valuable ingredients in the cosmetics industry.

Nutritional Supplements: Cordyceps is a rich source of proteins, amino acids, vitamins, and minerals, making it an excellent ingredient for nutritional supplements.

Stability Characteristics of Cordyceps Mycelium Extract

The stability of Cordyceps mycelium extract has been investigated, focusing on several key components:

Stability of Polysaccharide Extraction: Studies have compared the extraction efficiency of intracellular polysaccharides from Cordyceps mycelium using various methods, including alternating hot and cold maceration, hot water extraction, hydrochloric acid extraction, and sodium hydroxide extraction. Results indicated that alternating hot and cold maceration yielded the highest extraction rate, followed by hot water extraction, hydrochloric acid extraction, and sodium hydroxide extraction.

Stability of Carotenoids: The stability of carotenoids in Cordyceps was explored, revealing the presence of four highly water-soluble structures in ethanolic extracts: Cordyxanthin I, Cordyxanthin-II, Cordyxanthin-III, and Cordyxanthin-IV. Furthermore, the study found that the antioxidant activity of Cordyceps carotenoids obtained using different extraction methods showed no significant differences in vitro.

Stability and Safety of Nucleosides: An HPLC method was established to quantify five nucleosides (uridine, guanosine, adenosine, cordycepin, and N6-(2-hydroxyethyl)-adenosine) in Cordyceps, enabling the comparison of compositional differences and the identification of characteristic components. This provides a scientific basis for quality control of Cordyceps and its extracts. The study found that cordycepin was relatively stable, while N6-(2-hydroxyethyl)-adenosine was less stable under heat and acidic conditions.

Stability Characteristics of Polysaccharides: Cordyceps mycelium and its extracellular polysaccharides exhibited excellent thixotropy, thickening properties, salt tolerance, heat resistance, and pH stability. When stored at 60°C under oxidative conditions for 7 days, the lipid oxidation rate of 0.05% mycelium and its extracellular polysaccharides decreased to 18.8% and 19.8%, respectively, demonstrating their excellent stability.

Safety Assessment of Cordyceps Mycelium Extract

Safety assessments of Cordyceps mycelium extract have focused on several key areas:

Pharmacological Effects and Safety: As a medicinal fungus, Cordyceps exhibits various pharmacological effects, including those on the cardiovascular system and anti-tumor activity, and is generally considered safe. Some studies have reported adverse gastrointestinal reactions such as dry mouth, nausea, and diarrhea. Additionally, allergic reactions to Cordyceps, particularly strain CS-4, have been observed in some patients.

Dose-Related Studies: In patients with chronic kidney disease, dosages of Cordyceps can reach 3-6 grams per day. In clinical studies involving lung cancer, Cordyceps has been used in combination with chemotherapeutic agents. Another clinical trial compared the effects of Cordyceps (3.15 grams for 5 weeks) with placebo on physical performance. Generally, researchers consider a daily dosage of 3-4.5 grams of Cordyceps to be adequate, except for patients with severe liver disease.

Toxicological Studies: Cordyceps is considered a non-toxic medicinal mushroom. In animal models, even when administered intraperitoneally to mice at doses as high as 80 grams per kilogram of body weight per day, no fatalities were observed. In another study, oral administration of 10 grams per kilogram per day to rabbits for 3 months did not reveal any abnormalities in blood or liver and kidney function tests.

Precautions for Specific Populations: Caution is advised for patients undergoing antiviral or antidiabetic drug therapy, as Cordyceps contains hypoglycemic and antiviral agents that may interact with these medications.

(1) Raw Material Inspection:

Visual inspection for foreign matter, mold, and discoloration

Microscopic examination for fungal contaminants

Moisture content analysis

Heavy metal testing

(2) Extraction Process:

Choice of extraction method (e.g., hot water extraction, ultrasonic extraction, enzymatic extraction)

Optimization of extraction parameters (temperature, time, solvent ratio)

Filtration to remove insoluble particles

(3) Filtration and Concentration:

Filtration to remove impurities

Concentration to increase the concentration of bioactive compounds

(4) Drying and Milling:

Drying to remove moisture

Milling to obtain a fine powder

(5) Packaging:

Packaging in airtight containers to prevent contamination and degradation

(6) Quality Control Testing:

• Microbial testing: To ensure the absence of harmful microorganisms
• Heavy metal testing: To assess the levels of heavy metals, such as lead, mercury, and cadmium
• Pesticide residue testing: To check for pesticide residues
• Polysaccharide content: To determine the concentration of polysaccharides
• Cordycepin content: To measure the level of cordycepin
• Other bioactive compounds: To analyze the presence and quantity of other bioactive compounds, such as adenosine and cordycepic acid

(7) Release for Distribution: If all quality control tests are passed, the product is released for distribution.

What is Cordyceps mycelium extract powder?

Cordyceps mycelium extract powder is a natural product derived from the cultivated mycelium of Cordyceps sinensis. It is rich in bioactive compounds such as polysaccharides, cordycepin, and adenosine, known for their immune-boosting, anti-fatigue, and antioxidant properties.

Where does your Cordyceps mycelium extract come from?

Our Cordyceps mycelium extract is sourced from our own GMP-certified production facility. We employ superior strains and advanced cultivation techniques to ensure the purity and quality of our products.

What are the active ingredients in your product?

Our product is rich in various bioactive compounds, including polysaccharides, cordycepin, and adenosine. The specific content can be customized according to your requirements.

What are the specifications and packaging options available?

We offer a variety of specifications and packaging options, including bottles and bags, to meet your specific needs.

We have a comprehensive quality management system in place, with strict quality control measures at every stage from raw material procurement to finished product. We use advanced instruments such as HPLC and GC-MS to test our products for purity, content, and safety. Does your product comply with relevant regulations?

Our products comply with both domestic and international food safety standards and we can provide corresponding test reports.

Does your product contain any allergens?

Our product does not contain common allergens such as gluten or lactose, but we recommend that individuals with fungal allergies use it with caution.

Who is this product suitable for?

This product is suitable for individuals with low immunity, fatigue, or those seeking to improve overall health.

How can I order your product? You can contact us by phone, email, or online to inquire about our products and place an order.

Can I request a sample?

We can provide free samples for your testing and evaluation, however, shipping costs may apply.

Can I customize the product?

Yes, we can customize the product to meet your specific requirements, such as different specifications and potency.

What is the shelf life of your product? Our product has a shelf life of 2 years. Please store in a cool, dry place.

What shipping methods do you offer? We offer various shipping methods, such as express delivery and sea freight, to meet your specific needs.