Wormwood Extract Powder

Wormwood Extract Powder

CAS No.: 475-83-2
Other Names:Ice platform,grass,fragrant mugwort
Latin name: Artemisia argyi
Plant parts:Leaf
Appearance:Brown Powder
Specification:5:1, 10:1, 20:1
MOQ: 1kg
Features:Antiviral,antioxidant, immune regulation
Application:Medicine,daily chemicals,food, agriculture
Certificate:cGMP,ISO9001,ISO22000,HACCP,FDA,halal,USDA/EU Organic Certificates
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Description
Technical Parameters

Product Description

Mugwort, scientifically known as Artemisia argyi, is a plant of the Asteraceae family. It is widely distributed throughout China, especially in Qichun, Hubei, Nanyang, Henan, etc., where the cultivation of mugwort has a long history. Mugwort has a long history of application in China. It was first seen in "Famous Doctors' Records" and was used in traditional Chinese medicine treatments such as dispelling cold and relieving pain, warming the meridians and stopping bleeding. In ancient times, it was often used in traditional therapies such as moxibustion and moxa sticks to treat rheumatism, dysmenorrhea, colds and other symptoms.

Wormwood Extract Powder is mainly derived from the dried leaves of mugwort, which contains rich chemical components, including volatile oils, flavonoids, triterpenoids, etc. These components give mugwort unique pharmacological activity. It is now often used in the agricultural field as a natural feed additive to enhance the immunity of livestock and poultry.

Wormwood

Certificate of Analysis

Below is the COA of Wormwood Extract Powder, please refer to it.

Item

Specification

Result

Method

Basic Product Information

     

Latin Name

Artemisia argyi

Conform

/

Part of the Plant

Leafs

Conform

/

Country of Origin

China

Conform

/

Marker Compounds

     

Specification

10:1

Conform

UV/HPLC

Organoleptic Data

     

Appearance

Fine Powder

Conform

Organoleptic

Color

Brown

Conform

Organoleptic

Odor

Characteristic

Conform

Organoleptic

Physical Characteristics

     

Particle Size (80 mesh)

100%pass 80mesh

Conform

/

Moisture

≤5.0%

3.10%

GB 5009.3

Ash Content

≤5.0%

2.48%

GB 5009.4

Heavy Metals

     

Pesticides Residue (mg/kg)

<0.05

Conform

GB/T 5009.19

As

<2.0ppm Max.

Conform

GB 5009.11

Pb

<3.0ppm Max.

Conform

GB 5009.12

Cd

<1.0ppm Max.

Conform

GB 5009.15

Hg

<0.1ppm Max.

Conform

GB 5009.17

Microbiology

     

Total Plate Count

1000cfu/g

Conform

GB 4789.2

Total Yeast & Mold

100cfu/g

Conform

GB 4789.15

E.Coli

Negative

Negative

GB 4789.38

Salmonella

Negative

Negative

GB 4789.31

Shelf Life

24 months under the conditions above and in its original packaging.

Storage

Store in cool & dry place, keep away from strong light and heat.

 

Extraction Process

There are various methods for preparing wormwood extracts. Common extraction processes include:

  • Steam distillation: The volatile oil in wormwood is extracted through steam. This method is simple and low-cost.
  • Solvent extraction: Use ethanol and other solvents to heat and reflux wormwood multiple times. After extracting the effective ingredients, remove the residue and water to obtain a dark brown powder extract.
  • Supercritical fluid extraction: Utilize the high solubility of fluids such as supercritical carbon dioxide, the extraction efficiency is high, the cost is low and it is environmentally friendly, and it has gradually become the mainstream method.
  • Ultrasonic assisted extraction: Use the cavitation effect of ultrasound to accelerate the extraction process and improve the extraction efficiency.

Spray drying process flow chart

 

Active Compounds & Mechanisms

Artemisia absinthium produces a chemically complex secondary metabolite profile. The following table maps the primary constituent classes to their documented pharmacological mechanisms:

Compound Class

Key Representatives

Primary Bioactivity

Sesquiterpene Lactones

Absinthin, artabsin, anabsinthin

Bitter tonic, antiparasitic, anti-inflammatory, cytotoxic (preclinical)

Monoterpenes (volatile)

α-Thujone, β-thujone, camphor

CNS activity (GABA-A modulation); antimicrobial; regulatory-controlled

Flavonoids

Artemetin, casticin, quercetin, luteolin

Antioxidant, anti-inflammatory, hepatoprotective

Phenolic Acids

Chlorogenic acid, caffeic acid

Antioxidant, antimicrobial

Coumarins

Scopoletin, herniarin

Anti-inflammatory, antispasmodic

Polyacetylenes

Various C₁₃ and C₁₄ compounds

Antimicrobial, antiparasitic

Essential Oil

Thujone, sabinene, myrcene, cis-epoxyocimene

Antimicrobial, insect-repellent

Tannins

Condensed tannins

Astringent, antimicrobial, antidiarrheal

 

Main Effects And Functions

Antibacterial and antiviral
Anti-inflammatory effect
Antioxidant and anti-aging
Calming and tranquilizing
  • Antibacterial and antiviral: inhibit the growth of a variety of bacteria, fungi and viruses, prevent and assist in the treatment of infectious diseases.
  • Anti-inflammatory effect: by inhibiting inflammatory pathways, reducing inflammatory reactions, and relieving inflammation-related diseases.
  • Antioxidant and anti-aging: scavenging free radicals, reducing cell oxidative damage, and delaying the aging process.
  • Warming the meridians and stopping bleeding: warming the meridians and dispelling cold, promoting qi and relieving pain, can be used for deficiency-cold bleeding, such as dysmenorrhea, irregular menstruation, vomiting blood, blood in the stool, etc.
  • Immunomodulation: enhance the activity of the body's immune cells, improve immunity, and promote health.
  • Calming and tranquilizing: volatile oil components have a sedative effect, which can improve sleep quality and relieve anxiety.
  • Antiasthmatic and expectorant: relieve bronchospasm, reduce sputum secretion, suitable for respiratory diseases such as cough and asthma.
  • Hepatoprotective effect: improve liver function, reduce liver fibrosis, and protect liver health.
  • Anti-allergic: enhance anti-allergic ability, relieve skin problems such as allergic dermatitis and eczema.
  • Regulating blood lipids and blood sugar: improve blood lipid metabolism, lower blood sugar, and are beneficial to cardiovascular health.
  • Anti-obesity: regulate fat metabolism, reduce body fat accumulation, and assist in weight loss.
  • Promote wound healing: accelerate wound healing, reduce scar formation, and promote skin health.
  • Improve digestive function: relieve stomach discomfort, promote digestion, and is suitable for cold stomach, loss of appetite, etc.

Application Fields

Medical field

  • Used in the preparation of antiviral drugs, antibacterial drugs, anti-inflammatory drugs, etc.
  • Used in traditional Chinese medicine to treat colds, rheumatism, gynecological diseases, etc.
  • As moxibustion materials, it promotes blood circulation and enhances immunity.
  • Daily chemical field
  • Applied to antibacterial soaps, disinfectants, hand sanitizers, mouthwashes and other hygiene products.
  • Used in skin care products and cosmetics, such as creams, essences, shampoos, etc., to play an antioxidant and soothing role.

Food field

  • As a natural preservative and antioxidant, it is used in food processing.
  • Develop functional foods, such as wormwood tea, wormwood biscuits, wormwood wine, etc.

Health care products field

  • Make warming and tonic, gynecological disease conditioning, and immunity enhancement health products.
  • Used to develop health products with anti-inflammatory, antioxidant, and antibacterial effects.

Home textile field

  • Make wormwood pillows, bellybands, wormwood quilts, etc., which have antibacterial, anti-allergic, and blood circulation promoting effects.

Agricultural field

  • As a natural pesticide and insecticide, it is used for crop protection.

Environmental protection field

  • Used in the production of biodegradable plastics.
  • As a planting matrix, used to cultivate edible fungi or other crops.

Cultural and creative field

  • Develop cultural and creative products such as mugwort sachets and mugwort lanterns.
  • Create rural tourism projects with mugwort as the theme.

Building materials field

  • Mugwort fiber is used to produce environmentally friendly building materials, such as partition boards, floors, etc.

Bioenergy field

  • Make fuel pellets, produce biogas, etc.
Medical field Daily chemical field Food field Health care products field Environmental protection field

 

Comparison: Wormwood Extract vs. Competing Digestive Bitter Botanicals

Formulators developing digestive health, liver support, or antiparasitic products frequently evaluate wormwood against gentian, dandelion root, and artichoke leaf. Here is a specification-level comparison:

Parameter

Wormwood Extract

Gentian Root Extract

Dandelion Root Extract

Artichoke Leaf Extract

Primary Bitter Compounds

Absinthin, artabsin (sesquiterpene lactones)

Gentiopicrin, amarogentin (iridoids)

Taraxacin, taraxacerin

Cynarin, chlorogenic acid

Bitterness Intensity

✅ Extremely high

✅ Very high

Moderate

Moderate

Digestive Stimulation

✅ Strong

✅ Strong

Moderate

✅ Strong (bile)

Antiparasitic Activity

✅ Documented

Limited

Limited

Limited

Anti-inflammatory

✅ Strong

Moderate

✅ Moderate

✅ Strong

Hepatoprotective

✅ Documented

Moderate

✅ Documented

✅ Strong

Regulatory Complexity

Moderate-High (thujone)

Low

✅ Low

✅ Low

Consumer Recognition

High (historical)

Moderate

High

Moderate

EU Food-Compliant Grade

✅ Available

✅ Yes

✅ Yes

✅ Yes

Craft Spirits Application

✅ Established (absinthe)

✅ Established (bitters)

Limited

Limited

Wormwood Extract's unmatched bitterness intensity, documented antiparasitic activity, and established role in craft spirits and traditional bitters formulations give it a differentiated profile that no other digestive botanical fully replicates. The regulatory complexity around thujone is real but manageable - and Jiuyuan Bio's EU-compliant grade eliminates it entirely for food-category applications.

 

Jiuyuan Biotech Advantages

JIUYUAN BIOTECH is a well-known enterprise focusing on plant extracts and various nutritional health food raw materials, fruit and vegetable powders and other products. Our factory covers an area of more than 70,000 square meters. The hardware and software equipment includes 4 production workshops and multiple production lines, a professional R&D technology center and multiple advanced testing equipment. Therefore, the quality of the products is very guaranteed, and it has become the designated manufacturer for OEM for many domestic companies.

The company operates strictly in accordance with GMP operating specifications, and its products have multiple international qualifications and certifications, which greatly reduces the risk of customers choosing us. We are always committed to providing customers with high-quality products and services.

certification 2

 

Packaging & Transportation 

 

lQDPJwtZrxD2923NAjzNA1qwPujQkmzUYQgHLIUZvgIeAA858572

ByAir

100kg-1000kg, 5-7Days

Airport to airport service professional

clearance broker needed

lQDPJxnqnLSLN23NAjzNA1qwMj8Bbaib1ZwHLIUZvgIeAg858572

BySea

Over300kg, Around 30 Days

Port to port service professional

clearance broker needed

lQDPKGMvfZb4x23NAjzNA1qw2zuBMF7qYlcHLIUZvgIeAQ858572

Express

Under 100kg, 3-5Days

Door-to-door service easy to pick up the goods

We have a default packaging style to ensure that the product reaches the customer safely. Of course, if you have a specific packaging style or suggestion, please contact us and we will customize it for you.

product-1200-500

 

Buyer Guide

Wormwood extract is not a commodity botanical. Its regulatory profile, species authentication requirements, and thujone management complexity demand a more thorough supplier qualification process than most plant extracts. Here are the checkpoints that protect your formulation investment:

1. Specify Grade Based on Application and Target Market First The EU food-compliant grade (thujone ≤0.5 mg/kg) and the standard herbal extract grade serve fundamentally different regulatory pathways. Mixing up grades creates compliance exposure. Define your product category, target market, and applicable thujone limits before requesting quotes - not after.

2. Demand GC-MS Thujone Quantification - Not Just a Declaration Thujone content must be verified by GC-MS with α-thujone and β-thujone reported separately. A COA that lists "thujone: compliant" without quantified values is analytically insufficient for EU or US regulatory purposes. Insist on the full GC-MS report.

3. Verify Species Authentication Documentation Artemisia absinthium adulteration with related species (A. annua, A. vulgaris, A. pontica) is a documented supply chain risk. Request GC-MS volatile fingerprint data confirming species identity - not just macroscopic or TLC identification alone.

4. Understand Thujone Regulatory Limits by Market and Product Category

EU food products: ≤0.5 mg/kg (general foods); ≤10 mg/kg (alcoholic beverages >25% ABV) - EU Reg. 1334/2008

EU herbal supplements: HMPC monograph guidance applies; thujone limits vary by product form

USA: FDA classifies wormwood as GRAS for use in alcoholic beverages with thujone-free specification; supplement use requires careful claim structuring under DSHEA

Canada: NHP monograph available; thujone limits apply

Confirm applicable limits with your regulatory counsel for your specific product category

5. Harvest Stage Documentation Matters Absinthin content in A. absinthium varies significantly with harvest stage - early flowering material contains substantially higher sesquiterpene lactone concentrations than vegetative or post-flowering material. Ask your supplier to document harvest stage for each lot. If they cannot, the quality marker consistency of your ingredient is unverifiable.

6. Request Samples with Full Analytical Package We provide analytical samples (100–500 g) for qualified buyers, shipped with COA, HPLC chromatogram, GC-MS thujone report, TDS, and MSDS.

7. Plan for Formulation Challenges from Intense Bitterness Wormwood extract is among the most intensely bitter botanical ingredients commercially available. For capsule and tablet applications, bitterness is contained. For functional food, beverage, or powder sachet applications, taste-masking strategies (encapsulation, flavor pairing, dose optimization) are essential - factor this into your formulation timeline.

 

FAQ

Q1: What is the difference between Wormwood (Artemisia absinthium) and Sweet Wormwood (Artemisia annua)?

These are distinct species within the same genus with very different chemical profiles and applications. Artemisia absinthium (common wormwood) is characterized by sesquiterpene lactones (absinthin, artabsin) and thujone - the basis for its digestive bitter, antiparasitic, and traditional herbal applications. Artemisia annua (sweet wormwood) is the source of artemisinin - the antimalarial sesquiterpene lactone that earned the 2015 Nobel Prize in Physiology or Medicine. The two should never be confused in procurement or formulation. Our Wormwood Extract Powder is produced exclusively from authenticated Artemisia absinthium with GC-MS species verification per batch.

Q2: Is Wormwood Extract Powder safe for use in dietary supplements?

Artemisia absinthium has a long history of therapeutic use in European herbal medicine and is listed in multiple pharmacopoeial references. Published safety data supports its use at appropriate doses for short-term applications. The primary safety consideration is thujone content - α-thujone is a GABA-A receptor antagonist and is neurotoxic at high doses. EU and US regulatory frameworks address this through thujone limits in food applications. For supplement use, formulators should work within established dosing guidance from HMPC monographs or equivalent references, avoid prolonged high-dose use, and include appropriate contraindication labeling (pregnancy, lactation, epilepsy, kidney disease).

Q3: What are the primary applications of Wormwood Extract in supplement formulations?

The most substantiated supplement applications are: (1) digestive health - bitter tonic effects stimulating gastric secretion, bile flow, and digestive enzyme activity; (2) intestinal parasite management - antiparasitic activity of sesquiterpene lactones; (3) liver and bile support - choleretic and hepatoprotective effects; and (4) anti-inflammatory formulations - NF-κB suppression and cytokine modulation. Traditional European herbal medicine also supports use for loss of appetite and functional dyspepsia.

Q4: What is the EU regulatory status of Wormwood Extract in food and beverages?

Under EU Regulation 1334/2008 on food flavorings, thujone (from Artemisia species) is permitted in food and beverages at specified maximum levels: ≤0.5 mg/kg in general foods, ≤10 mg/kg in alcoholic beverages with >25% ABV, and ≤35 mg/kg in bitters. Wormwood (A. absinthium) itself is listed as a source plant subject to these thujone restrictions. Our EU food-compliant grade is produced and analytically verified to meet the ≤0.5 mg/kg limit for general food applications. For herbal supplement applications in the EU, the EMA HMPC has published a community herbal monograph for Artemisia absinthium covering traditional use indications.

Q5: How do you authenticate Artemisia absinthium and prevent species adulteration?

Authentication is performed in three layers: (1) macroscopic examination of raw material against botanical reference standards; (2) TLC fingerprinting against authenticated reference extracts; and (3) GC-MS volatile profile analysis - the most definitive method for distinguishing A. absinthium from related species including A. vulgaris, A. pontica, and A. annua, which have distinct terpene profiles. All three methods are applied to every incoming raw material lot before processing begins. GC-MS authentication reports are available to buyers upon request.

Q6: Can Wormwood Extract Powder be used in craft spirits and bitters formulations?

Yes - this is one of wormwood's most established commercial applications. Artemisia absinthium is a defining botanical in absinthe production and a traditional ingredient in vermouth and herbal bitters. For these applications, our EU food-compliant grade (thujone ≤0.5 mg/kg for general food; specific limits apply for spirits) is the appropriate specification. Buyers developing spirits or bitters products should confirm applicable thujone limits under their national spirits regulations, as limits vary between EU member states and the USA (TTB regulations).

Q7: What is the recommended storage condition for Wormwood Extract Powder?

Store in a cool (below 25°C), dry environment away from direct sunlight, heat, and strong oxidizing agents. Sesquiterpene lactones are susceptible to oxidative degradation under UV exposure - light-protective packaging is standard for our product. Keep drums sealed until use; once opened, reseal tightly and consume within 3 months. Under proper storage conditions, shelf life is 24 months from the date of manufacture.

Q8: How does Jiuyuan Bio manage batch-to-batch consistency for a botanically variable ingredient like Wormwood Extract?

Consistency is maintained through four mechanisms: (1) contracted cultivation bases or verified wild-harvest sources with documented harvest timing protocols; (2) HPLC pre-screening of incoming raw material for sesquiterpene lactone content, with rejection of below-specification lots; (3) in-process HPLC and GC-MS monitoring at extraction and concentration stages; and (4) finished product HPLC assay against validated absinthin reference standards before batch release. Long-term supply agreement customers receive additional batch consistency guarantees in their supply contracts.

 

Request a Sample or Commercial Quote

Jiuyuan Biotech supplies Wormwood Extract Powder to food manufacturers, supplement brands, and contract formulators across North America, Europe, and the Asia-Pacific region. Our technical team - not a generic sales inbox - handles every inquiry.

Email: info@jiuyuanbio.com

Website: www.jiuyuanbio.com

Request: Sample| Bulk Quote | CoA & Spec Sheet | Custom Carrier Ratio

Standard response time: within 1 business day. Please include your target application and annual volume estimate for the most relevant technical recommendation.

 

 

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